Can people with Sotos syndrome live a normal life? Sotos syndrome is not a life-threatening disorder and patients may have a normal life expectancy. The initial abnormalities of Sotos syndrome usually resolve as the growth rate becomes normal after the first few years of life.
Sotos syndrome is not a life-threatening disorder and patients may have a normal life expectancy. The initial abnormalities of Sotos syndrome usually resolve as the growth rate becomes normal after the first few years of life.
Is Sotos syndrome a disability?
People with Sotos syndrome often have intellectual disability, and most also have behavioral problems.
How many people have Soto syndrome?
Sotos Syndrome is a rare overgrowth condition that causes quick growth in early childhood resulting in children being considerably taller than their peers. It affects between1 in 10,000 and 1 in 14,000 new-born babies.
Is Sotos syndrome a form of autism?
Sotos syndrome and autism spectrum disorder (ASD) are different conditions. But they both have some of the same symptoms, which could lead to a misdiagnosis. Sotos syndrome is a genetic condition caused by a gene mutation and ASD is a neurodevelopmental condition, which many times has an unknown cause.
Can people with Sotos syndrome live a normal life? – Related Questions
Is Sotos syndrome neurological?
Sotos syndrome is a genetic disorder, described in 1964, characterized by excessive growth before and after birth, a large, elongated (dolichocephalic) head, distinctive facial configuration, and a non-progressive neurological disorder with intellectual disability.
Which parent carries autism gene?
Due to its lower prevalence in females, autism was always thought to have a maternal inheritance component. However, research also suggests that the rarer variants associated with autism are mostly inherited from the father.
What is reverse Sotos syndrome?
Sotos syndrome is a disorder of childhood overgrowth caused by NSD1 deletions. Duplications involving NSD1 cause a ‘reverse Sotos syndrome’ phenotype characterised by short stature and microcephaly. The contrasting phenotypes of NSD1 deletions and duplications suggest a dose effect.
However, brain abnormalities in Sotos syndrome are nonspecific (Tatton-Brown et al., 2005) and many fetuses with Sotos syndrome will not be large for gestational age at the time of level II sonographic examination (16–20 weeks), making it very difficult to diagnose this condition prenatally.
What are Soto seizures?
The seizure phenotype in Sotos syndrome most commonly involves staring spells, afebrile tonic‐clonic seizures or febrile convulsions; however, other seizure types may occur. Seizures are typically well‐controlled with medication, but drug‐resistant epilepsy occurs in a minority.
Who discovered Sotos syndrome?
Sotos syndrome was first described in 1964 by Juan Sotos and the major diagnostic criteria of a distinctive facial appearance, childhood overgrowth and learning disability were established in 1994 by Cole and Hughes. In 2002, cloning of the breakpoints of a de novo t(5;8)(q35;q24.
What is Solo disease?
Disease Solo is a one-player version of the HubNet activity Disease. It simulates the spread of a disease through a population. One agent in the population is a person controlled by the user; the others are “androids” controlled by the computer.
Why is it called Kabuki syndrome?
The name of this disorder comes from the resemblance of its characteristic facial appearance to stage makeup used in traditional Japanese Kabuki theater. People with Kabuki syndrome have mild to severe developmental delay and intellectual disability.
