When was the first typhus vaccine invented?

When was the first typhus vaccine invented?

The first typhus vaccines were developed in the 1970s using crude antigen or formalin-killed R. prowazekii. Although they provided some level of protection, they were only indicated for those at the highest risk of acquiring epidemic typhus, and they had undesirable toxic reactions and difficulties in standardization.

How was the typhus vaccine created?

Weigl created a technique that involved raising millions of infected lice in a laboratory and harvesting their guts to get the materials for a vaccine. Lice that had been infected with typhus bacteria would be allowed to feed on human volunteers, says Arthur Allen, who wrote the new book The Fantastic Laboratory of Dr.

Who discovered typhus?

In 1909 French microbiologist, director of the Pasteur Institute in Tunis Charles Nicolle discovered the ways of the louse-borne typhus infection. With his numerous experiments on apes he proved that body louse is a transmitting gent of louse-borne infection.