What does something’s up mean?

What does something’s up mean?

something strange is happening. See full dictionary entry for up.

Is something up in a sentence?

She noticed that something was up and she came over to see me.

What does it mean if something is up and down?

Definition of up-and-down (Entry 1 of 2) 1 : marked by alternate upward and downward movement, action, or surface. 2 : perpendicular.

What does it mean to get f * * * * * Up?

vulgar slang : intoxicated from drugs or alcohol.