What causes scleroderma?

What causes scleroderma?

Scleroderma results from an overproduction and accumulation of collagen in body tissues. Collagen is a fibrous type of protein that makes up your body’s connective tissues, including your skin. Doctors don’t know exactly what causes this process to begin, but the body’s immune system appears to play a role.

What’s the meaning of scleroderma?

Scleroderma is an autoimmune connective tissue and rheumatic disease that causes inflammation in the skin and other areas of the body. When an immune response tricks tissues into thinking they are injured, it causes inflammation, and the body makes too much collagen, leading to scleroderma.

What did Bob Saget have to do with scleroderma?

Saget directed the 1996 TV movie For Hope, about a young woman with scleroderma based on Gay’s experience, which helped raise awareness of the disease.

What were your first signs of scleroderma?

Thickening and swelling of the fingers. Pale fingers that may become numb and tingle when exposed to cold or stress, known as Raynaud’s phenomenon. Joint pain. Taut, shiny, darker skin on large areas, which can cause problems with movement.