Why can’t Red Skull hold the Tesseract?

In The First Avenger, Red Skull obtains the Tesseract (the Space Stone) and uses it to make weapons for Hydra, an offshoot of the Third Reich. At the climax of the film, after fighting with Captain America (Chris Evans), the Tesseract becomes unstable and when Red Skull tries to grab it, it shoots him into the cosmos.

How did Red Skull end up guarding the soul stone?

Red Skull’s appearance as keeper of the Soul Stone in Avengers: Infinity War was a shocking cameo for many Marvel fans. After trying in vain to capture the Tesseract, also known as the Space Stone, he was cursed to keep watch over the cliffs of Vormir as those who seek the Soul Stone sacrifice someone they love.

How was the Tesseract recovered?

Eventually, it was brought to Earth and left in Tønsberg, where it was guarded by devout Asgardian worshipers. In 1942, the Tesseract was retrieved by Johann Schmidt, the leader of HYDRA, who used the Tesseract to power enhanced weaponry in order to defeat the Allies during World War II.